Pharmacokinetic Analysis and Uptake of 18F-FBPA-Fr After Ultrasound-Induced Blood–Brain Barrier Disruption for Potential Enhancement of Boron Delivery for Neutron Capture Therapy
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چکیده
منابع مشابه
An investigation into the potential applicability of gel dosimeters for dosimetry in boron neutron capture therapy
Background: The aim of this work was to establish how well gel dosimeters performed, as substitutes for brain tissue compared with standard phantom materials such as water, polymethyl-methacrylate (or PMMA), A150 plastic and TE- liquid phantom material for dosimetry of neutron beams in boron neutron capture therapy. Materials and Methods: Thermal neutron fluence, photon dose and epithermal neu...
متن کاملDesign and Simulation of Photoneutron Source by MCNPX Monte Carlo Code for Boron Neutron Capture Therapy
Introduction Electron linear accelerator (LINAC) can be used for neutron production in Boron Neutron Capture Therapy (BNCT). BNCT is an external radiotherapeutic method for the treatment of some cancers. In this study, Varian 2300 C/D LINAC was simulated as an electron accelerator-based photoneutron source to provide a suitable neutron flux for BNCT. Materials and Methods Photoneutron sources w...
متن کاملInvestigation the potential of Boron neutron capture therapy (BNCT) to treat the lung cancer
Introduction: Boron neutron capture therapy (BNCT) is recommended to treat the glioblastoma tumor. It is well known that neuron beams are more effective treatment than photon beams to treat hypoxia tumors due to interaction of neutron with nucleus and production of heavy particles such as 7Li and alpha particle. In this study to evaluate the suitability of BNCT for treating of ...
متن کاملA Monte Carlo study of SPECT in boron neutron capture therapy for a heterogeneous human phantom
Background: Boron neutron capture therapy (BNCT) is a binary radiotherapy combining biochemical targeting with neutron irradiation. However, monitoring the boron distribution is a fundamental problem in BNCT. Prompt gamma rays emitted by boron capture reaction can be used to address the issue. Materials and Methods: The general-purpose Monte Carlo toolkits Geant4 and MCNP were used for the simu...
متن کاملan investigation into the potential applicability of gel dosimeters for dosimetry in boron neutron capture therapy
background: the aim of this work was to establish how well gel dosimeters performed, as substitutes for brain tissue compared with standard phantom materials such as water, polymethyl-methacrylate (or pmma), a150 plastic and te- liquid phantom material for dosimetry of neutron beams in boron neutron capture therapy. materials and methods: thermal neutron fluence, photon dose and epithermal neut...
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ژورنال
عنوان ژورنال: Journal of Nuclear Medicine
سال: 2014
ISSN: 0161-5505,2159-662X
DOI: 10.2967/jnumed.113.125716